Gene Testing for cancer target-drug

Genetic testing can provide an accurate assessment of the suitability of target drugs and avoid ineffective treatment and medical waste of resources. There are specific Genes for specific drugs, therefore the clinical physicians may take the medication reference based on the gene examination result.

Genes and medicine comparison as bellow:

Cancer

Drug

Gene

Non Small Cell Lung Cancer

Irresa

EGFR

Colorectal Cancer

Erbitux

KRAS/NRAS

Chronic Myeloid Leukemia

Imatinib or Nilotinib

BCR-ABL

GIST

Imatinib or Sunitinib

CKit/ PDGFRA

 

Technical method is using Real-Time PCR and Sanger sequencing and sensitivity is up to 1%.

Process:

genetic consulting --> filling in the consent form --> FFPE sample --> analysis in the LAB --> report consulting with clinician